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A week away from leaving for his first year of college, Michael starts to become frustrated with his parent's overprotective tendencies toward his teen brother Nathan, who has Down syndrome.
Sam O'Byrne, Trevor Barella, Bettina Devin, Ross Turner, George McRae, Karen Kahn, Wyatt Tithof, Jenna Herz, Jessica Sarah Flaum, Rosie Cruz, Sophia Martin, Robert Matas

Following the death of a hotelier in Punta del Este, Uruguay, an unexpected inheritance dispute begins. Stallone, an actor with Down syndrome, believes he is the rightful heir to the hotel. On the other side is Magrelo, a young autistic man who was raised as an adopted son by the deceased. Without waiting for the reading of the will, Stallone decides to reunite his old friends with Down syndrome from the institute where they lived in Brazil to spend a week's vacation at the hotel.
2026

It explores themes of love, acceptance and self-discovery through the story of two individuals, Jiro and Jessica, who have down syndrome.
2026

Vito is a sweet little boy with Down syndrome, and this short documentary puts his energetic, jolly personality on full display as he interacts with his loving family. By showing Vito’s dignity and inherent value, Vito-Man tackles the difficult conversation that is the eradication of people with Down syndrome, proving that an extra chromosome should not be a death sentence.
2024

Alba has Down's Syndrome and was left in the hospital when she was born. Thirty families rejected her before the court decided to entrust her to Luca: a Catholic — and gay — single man.
2023

Valentina is fed up of her Down’s syndrome, convinced that it prevents her from making her dream true: becoming a trapeze artist. But a magical journey will reveal to her all that she is capable of doing.
2021

A young woman with Down Syndrome begins a journey chases her dream of becoming a mechanic, despite being held back by the person she trusts the most.
2021

After losing his mother, a boy with Down syndrome takes his trunk of magical costumes to live with his grandparents in this animated tale.
2021

Jess is thrilled to be the surrogate for her best friend and his husband, but when a prenatal test comes back, it creates a moral dilemma that threatens their friendship.
2021

Happy newlyweds Ida and Jura are expecting a child. Ida suddenly finds out that the child will be special. She is unsure of how Jura will react when he learns the news, or what life with an extraordinary child will bring.
2019

A down-on-his-luck crab fisherman embarks on a journey to get a young man with Down syndrome to a professional wrestling school in rural North Carolina and away from the retirement home where he’s lived for the past two and a half years.
2019

The Senior Prank is family drama about a group of popular teenagers who wage a fake campaign to elect a girl with Down Syndrome as the schools Homecoming Queen. Inspired by real bullying events witnessed by real teenagers in their local high schools.
2014

A father fears the sexual awakening of his disabled son, a teenager living with Down syndrome, and struggles with the notion of letting him grow up.
2012

between cigarettes and religion
2011

During a blizzard in 1964, Dr. David Henry delivers his son Paul with the help of nurse Caroline. But when Henry realizes his wife is also carrying a girl with Down syndrome, he hands the second child over to Caroline without his wife's knowledge. Henry's fateful decision yields grave consequences for his family over the next 20 years.
2008

The adventures of a young man whose principle interests are snails, salt, a pipe, and how to get home. As tormented by a hubristic, racist inner psyche.
2005

Georges has Down syndrome, living at a mental-institution, Harry is a busy businessman, giving lectures for young aspiring salesmen. He is successful in his business life, but his social life is a disaster since his wife left him and took their two children with her. This weekend his children came by train to meet him, but Harry, working as always, forgot to pick them up. Neither his wife or his children want to see him again and he is driving around on the country roads, anguished and angry. He almost runs over Georges, on the run from the institution since everybody else went home with their parents except him, whose mother is dead. Harry tries to get rid of Georges but he won't leave his new friend. Eventually a special friendship forms between the two of them, a friendship which makes Harry a different person.
1996

In the beginning of the 19th century, Johannes Elias Alder is born in a small village in the Austrian mountains. While growing up he is considered strange by the other villagers and discovers his love of music, especially rebuilding and playing the organ at the village church. After experiencing an "acoustic wonder", his eye color changes and he can hear even the most subtle sounds.
1995

At The Kingdom, Denmark's most technologically advanced hospital, a number of strange and otherworldly events begin occurring, much to the dismay of its doctors and patients. A ghostly ambulance appears and disappears, the voice of a little girl calls to a patient in an elevator shaft, and a doctor's fetus begins growing at an alarming rate.
1994
Inspired by an extraordinary true story, Caden Cox made history by becoming the first person with Down syndrome to play and score in a college football game.

A woman attempts to stop her daughter signing away her down syndrome grandson for adoption. Based on a true story.
1993